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Wednesday, February 03, 2016

Huge cancer breakthrough as scientists kill infected cells by getting them addicted to drugs

http://www.mirror.co.uk/news/uk-news/huge-cancer-breakthrough-scientists-kill-7290940?ICID=ref_fark

The technique, called “mito-priming”, has been hailed by researchers as a breakthrough in the fight against the killer disease.
Scientists at the Beatson Institute in Glasgow, which is run by Cancer Research UK and closely linked to Glasgow University, developed the “significant” technique as a research tool while trying to understand how cancer cells die.
The technique could be applied to identify new anti-cancer drugs, such as so-called “BH3-mimetics” medications, and screen their effectiveness.
BH3-mimetics, a “very promising” new class of cancer drugs developed to specifically kill tumour cells, target a family of proteins called BCL-2 proteins, which function to keep cancer cells alive.
While not yet in use in clinical practice, BH3-mimetic anti-cancer drugs are showing great promise in late-stage clinical trials, particularly in the treatment of chronic lymphocytic leukaemia (CLL).

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