The researchers wanted to investigate if their discovery could have
an effect on how we treat disorders such as lung inflammation, bleeding,
and transplantation in the future, by transplanting lungs with
fluorescent megakaryocyte progenitor cells into mice with low platelet
The transplants produced a massive burst of platelets that quickly
restored the depleted platelet counts to normal levels, and the effect
lasted for several months.
Another experiment tested what would happen if the bone marrow wasn't playing a role in blood production.
The team implanted lungs with fluorescent megakaryocyte progenitor
cells into mice that had been engineered to have no blood stem cells in
their bone marrow.
So how did we miss such a crucial biological process this whole time? Time to rewrite the text books and above all ladies and gentlemen...Take deep breaths :)